SILVER-PORE

Silver-Pore is an owner technology of surface engineering projected to integrate the silver ions in the implant’s surface.

Silver ions are released in a controlled and gradually way, contributing to decrease the bacterial colonization and the biofilm formation, without modify the mechanical characteristics of the implant.

Advanced protection, integrated in the surface.

KEY CONCEPTS OF SILVER-PORE

  • Owner technologies of surface engineering
  • Controlled release of silver ions (Ag+)
  • Helps to prevent the colonization and the biofilm formation
  • Integration of silver ions on the implant’s surface
  • Industrial process repeatable and controlled
  • Developed with years of research and experimental evaluation

MECHANISM OF ACTION

Silver-Pore surface is designed to allow the release of silver ions (Ag+)

  1. Silver ions are integrated in the surface
  2. Silver ions are released in a controlled and active way over time
  3. Bacterial colonization and biofilm formation are reducted

ENGINEERED SURFACE TECHNOLOGY

Silver-Pore is an owner process that integrates silver ions (Ag +) directly on the implant’s surface, without additive coatings

  • Surface integration of ions Ag+
  • Controlled and prolonged release
  • Preservation of mechanical properties of the implant
  • Repeatable and industrialise process

REFERENCES

A Silver Ion-doped Calcium Phosphate-based Ceramic Nanopowder-coated Prosthesis Increased Infection Resistance  – Kose, Nusret ; Otuzbir, Ali ; Pekşen, Ceren ; Kiremitçi, Abdurrahman ; Doğan, Aydın Clinical Orthopaedics and Related Research®, 2013, Vol.471(8), pp.2532-2539 [Peer Reviewed Journal]

Silver Nanocoating Technology in the Prevention of Prosthetic Joint Infection – Gallo. Jiri; Panacek, Ales; Prucek, Robert; Kriegova, Eva; Hradilova, Sarka; Hobza, Martin; Holinka, Martin Materials, Vol.9(5), p.337 [Peer Reviewed Journal].

Development of a hydroxyapatite coating containing silver for the prevention of peri‐prosthetic infection – Ghani, Yaser ; Coathup, Melanie J. ; Hing, Karin A. ; Blunn, Gordon W. Journal of Orthopaedic Research, March 2012, Vol.30(3), pp.356-363 [Peer Reviewed Journal]

Silver ion doped ceramic nano-powder coated nails prevent infection in open fractures: In vivo study – Kose, Nusret ; Çaylak, Remzi ; Pekşen, Ceren ; Kiremitçi, Abdurrahman ; Burukoglu, Dilek ; Koparal, Savaş ; Doğan, Aydın Injury, February 2016, Vol.47(2), pp.320-324 [Peer Reviewed Journal]

Reduction of periprosthetic infection with silver‐coated megaprostheses in patients with bone sarcoma – Hardes, Jendrik ; Von Eiff, Christof ; Streitbuerger, Arne ; Balke, Maurice Budny, Tymoteus ; Henrichs, Marcel P. ; Hauschild, Gregor ; Ahrens, Helmut Journal of Surgical Oncology, 01 April 2010, Vol.101(5), pp.389-395 [Peer Reviewed Journal]

Silver-coated megaendoprostheses in a rabbit model—an analysis of the infection rate and toxicological side effects – Gosheger, Georg ; Hardes, Jendrik ; Ahrens, Helmut ; Streitburger, Arne ; Buerger, Horst ; Erren, Michael ; Gunsel, Andreas ; Kemper, Fritz H ; Winkelmann, Winfried ; Von Eiff, Christof Biomaterials, 2004, Vol.25(24), pp.5547-5556 [Peer Reviewed Journal]

Silver-coated endoprosthetic replacement of the proximal humerus in case of tumour—is there an increased risk of periprosthetic infection by using a trevira tube? – Schmolders, Jan ; Koob, Sebastian ; Schepers, Paul ; Kehrer, Michael ; Frey, Sönke ; Wirtz, Dieter ; Pennekamp, Peter ; Strauss, Andreas International Orthopaedics, 2017, Vol.41(2), pp.423-428 [Peer Reviewed Journal]

Lower limb reconstruction in tumor patients using modular silver-coated megaprostheses with regard to perimegaprosthetic joint infection: a case series, including 100 patients and review of the literature – Schmolders, J. ; Koob, S. ; Schepers, P. ; Pennekamp, P. ; Gravius, S. ; Wirtz, D. ; Placzek, R. ; Strauss, A. Archives of Orthopaedic and Trauma Surgery, 2017, Vol.137(2), pp.149-153 [Peer Reviewed Journal]

Silver-coated (Agluna®) tumour prostheses can be a protective factor against infection in high risk failure patients – Parry, Michael C ; Laitinen, Minna K ; Albergo, Jose I ; Gaston, Czar L ; Stevenson, Jonathan D ; Grimer, Robert J ; Jeys, Lee M European Journal of Surgical Oncology, April 2019, Vol.45(4), pp.704-710 [Peer Reviewed Journal]