{"id":12692,"date":"2020-01-23T10:39:55","date_gmt":"2020-01-23T09:39:55","guid":{"rendered":"https:\/\/www.permedica.it\/?page_id=12692"},"modified":"2026-07-14T15:20:03","modified_gmt":"2026-07-14T13:20:03","slug":"silver-pore","status":"publish","type":"page","link":"https:\/\/www.permedica.it\/en\/innovation-systems\/silver-pore\/","title":{"rendered":"SILVER-PORE"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 hundred-percent-fullwidth non-hundred-percent-height-scrolling fusion-equal-height-columns\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:0px;--awb-padding-right:0px;--awb-padding-bottom:0px;--awb-padding-left:0px;--awb-margin-top:60px;--awb-margin-bottom:0px;--awb-flex-wrap:wrap;\" id=\"pre-intervento\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_2 1_2 fusion-one-half fusion-column-first\" style=\"--awb-bg-image:url(&#039;https:\/\/www.permedica.it\/wp-content\/uploads\/2023\/03\/imaggine-silver-1024x717.jpg&#039;);--awb-bg-position:center center;--awb-bg-size:cover;--awb-margin-bottom:0px;\" data-scroll-devices=\"small-visibility,medium-visibility,large-visibility\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy fusion-empty-column-bg-image fusion-column-has-bg-image\" data-bg-url=\"https:\/\/www.permedica.it\/wp-content\/uploads\/2023\/03\/imaggine-silver-1024x717.jpg\"><img decoding=\"async\" class=\"fusion-empty-dims-img-placeholder fusion-no-large-visibility\" aria-label=\"Silver nanoparticles illustration\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271024%27%20height%3D%27717%27%20viewBox%3D%270%200%201024%20717%27%3E%3Crect%20width%3D%271024%27%20height%3D%27717%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\"><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_2 1_2 fusion-one-half fusion-column-last\" style=\"--awb-padding-top:11%;--awb-padding-right:11%;--awb-padding-bottom:11%;--awb-padding-left:11%;--awb-bg-size:cover;--awb-margin-bottom:0px;width:48%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy\"><div class=\"fusion-title title fusion-title-1 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-four\" style=\"--awb-text-color:#ed1c24;--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:20px;--awb-margin-left-small:0px;\"><h4 class=\"fusion-title-heading title-heading-center\" style=\"margin:0;\">SILVER-PORE<\/h4><\/div><div class=\"fusion-text fusion-text-1\"><p>Silver-Pore is an owner technology of surface engineering projected to integrate the silver ions in the implant\u2019s surface.<\/p>\n<p>Silver ions are released in a controlled and gradually way, contributing to decrease the bacterial colonization and the biofilm formation, without modify the mechanical characteristics of the implant.<\/p>\n<p>Advanced protection, integrated in the surface.<\/p>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 hundred-percent-fullwidth non-hundred-percent-height-scrolling fusion-equal-height-columns\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:0px;--awb-padding-right:0px;--awb-padding-bottom:0px;--awb-padding-left:0px;--awb-margin-top:0px;--awb-margin-bottom:0px;--awb-flex-wrap:wrap;\" id=\"ospedale\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_2 1_2 fusion-one-half fusion-column-first\" style=\"--awb-padding-top:5%;--awb-padding-right:11%;--awb-padding-bottom:5%;--awb-padding-left:11%;--awb-bg-color:#ffffff;--awb-bg-color-hover:#ffffff;--awb-bg-size:cover;--awb-margin-bottom:0px;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy\"><div class=\"fusion-title title fusion-title-2 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-four\" style=\"--awb-text-color:#ed1c24;--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:20px;--awb-margin-left-small:0px;\"><h4 class=\"fusion-title-heading title-heading-center\" style=\"margin:0;\">KEY CONCEPTS OF SILVER-PORE<\/h4><\/div><div class=\"fusion-text fusion-text-2\"><ul>\n<li>Owner technologies of <strong>surface engineering<\/strong><\/li>\n<li>Controlled release of <strong>silver ions (Ag+)<\/strong><\/li>\n<li>Helps to <strong>prevent the colonization and the biofilm formation<\/strong><\/li>\n<li>Integration of <strong>silver ions on the implant\u2019s surface<\/strong><\/li>\n<li>Industrial process <strong>repeatable<\/strong> and <strong>controlled<\/strong><\/li>\n<li>Developed with <strong>years of research<\/strong> and experimental evaluation<\/li>\n<\/ul>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_1_2 1_2 fusion-one-half fusion-column-last\" style=\"--awb-padding-top:5%;--awb-padding-right:11%;--awb-padding-bottom:5%;--awb-padding-left:11%;--awb-bg-color:rgba(0,0,0,0.05);--awb-bg-color-hover:rgba(0,0,0,0.05);--awb-bg-size:cover;--awb-margin-bottom:0px;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy\"><div class=\"fusion-title title fusion-title-3 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-four\" style=\"--awb-text-color:#ed1c24;--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:20px;--awb-margin-left-small:0px;\"><h4 class=\"fusion-title-heading title-heading-center\" style=\"margin:0;\">MECHANISM OF ACTION<\/h4><\/div><div class=\"fusion-text fusion-text-3\"><p style=\"text-align: justify;\">Silver-Pore surface is designed to <strong>allow the release of silver ions (Ag+)<\/strong><\/p>\n<ol>\n<li>Silver ions are integrated in the surface<\/li>\n<li>Silver ions are released in a controlled and active way over time<\/li>\n<li>Bacterial colonization and biofilm formation are reducted<\/li>\n<\/ol>\n<\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-separator fusion-full-width-sep\" style=\"margin-left: auto;margin-right: auto;width:100%;\"><\/div><div class=\"fusion-sep-clear\"><\/div><div class=\"fusion-text fusion-text-4\"><p>ENGINEERED SURFACE TECHNOLOGY<\/p>\n<p>Silver-Pore is an owner process that integrates silver ions (Ag +) directly on the implant\u2019s surface, without additive coatings<\/p>\n<ul>\n<li>Surface integration of ions Ag+<\/li>\n<li>Controlled and prolonged release<\/li>\n<li>Preservation of mechanical properties of the implant<\/li>\n<li>Repeatable and industrialise process<\/li>\n<\/ul>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-3 hundred-percent-fullwidth non-hundred-percent-height-scrolling fusion-equal-height-columns\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:0px;--awb-padding-right:0px;--awb-padding-bottom:0px;--awb-padding-left:0px;--awb-margin-top:0px;--awb-margin-bottom:0px;--awb-flex-wrap:wrap;\" id=\"post-intervento\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-4 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last fusion-column-no-min-height\" style=\"--awb-padding-top:11%;--awb-padding-right:11%;--awb-padding-bottom:11%;--awb-padding-left:11%;--awb-bg-color:rgba(0,0,0,0.05);--awb-bg-color-hover:rgba(0,0,0,0.05);--awb-bg-size:cover;--awb-margin-bottom:0px;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-column-wrapper-legacy\"><div class=\"fusion-title title fusion-title-4 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-four\" style=\"--awb-text-color:#ed1c24;--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:20px;--awb-margin-left-small:0px;\"><h4 class=\"fusion-title-heading title-heading-center\" style=\"margin:0;\">REFERENCES<\/h4><\/div><div class=\"fusion-text fusion-text-5\"><p><b>A Silver Ion-doped Calcium Phosphate-based Ceramic <\/b><b>Nanopowder<\/b><b>-coated Prosthesis Increased Infection Resistance\u00a0 <\/b>&#8211; Kose, Nusret ; Otuzbir, Ali ; Pek\u015fen, Ceren ; Kiremit\u00e7i, Abdurrahman ; Do\u011fan, Ayd\u0131n Clinical Orthopaedics and Related Research\u00ae, 2013, Vol.471(8), pp.2532-2539 [Peer Reviewed Journal]<\/p>\n<p style=\"text-align: justify; line-height: 2;\"><strong>Silver Nanocoating Technology in the Prevention of Prosthetic Joint Infection<\/strong> &#8211; Gallo. Jiri; Panacek, Ales; Prucek, Robert; Kriegova, Eva; Hradilova, Sarka; Hobza, Martin; Holinka, Martin Materials, Vol.9(5), p.337 [Peer Reviewed Journal].<\/p>\n<p><b>Development of a hydroxyapatite coating containing silver for the prevention of peri\u2010prosthetic infection <\/b>&#8211; Ghani, Yaser ; Coathup, Melanie J. ; Hing, Karin A. ; Blunn, Gordon W. Journal of Orthopaedic Research, March 2012, Vol.30(3), pp.356-363 [Peer Reviewed Journal]<\/p>\n<p><b>Silver ion doped ceramic nano-powder coated nails prevent infection in open fractures: In vivo study <\/b>&#8211; Kose, Nusret ; \u00c7aylak, Remzi ; Pek\u015fen, Ceren ; Kiremit\u00e7i, Abdurrahman ; Burukoglu, Dilek ; Koparal, Sava\u015f ; Do\u011fan, Ayd\u0131n Injury, February 2016, Vol.47(2), pp.320-324 [Peer Reviewed Journal]<\/p>\n<p><b>Reduction of periprosthetic infection with silver\u2010coated <\/b><b>megaprostheses<\/b><b> in patients with bone sarcoma <\/b>&#8211; Hardes, Jendrik ; Von Eiff, Christof ; Streitbuerger, Arne ; Balke, Maurice Budny, Tymoteus ; Henrichs, Marcel P. ; Hauschild, Gregor ; Ahrens, Helmut Journal of Surgical Oncology, 01 April 2010, Vol.101(5), pp.389-395 [Peer Reviewed Journal]<\/p>\n<p><b>Silver-coated <\/b><b>megaendoprostheses<\/b><b> in a rabbit model\u2014an analysis of the infection rate and toxicological side effects <\/b>&#8211; Gosheger, Georg ; Hardes, Jendrik ; Ahrens, Helmut ; Streitburger, Arne ; Buerger, Horst ; Erren, Michael ; Gunsel, Andreas ; Kemper, Fritz H ; Winkelmann, Winfried ; Von Eiff, Christof Biomaterials, 2004, Vol.25(24), pp.5547-5556 [Peer Reviewed Journal]<\/p>\n<p><b>Silver-coated <\/b><b>endoprosthetic<\/b><b> replacement of the proximal humerus in case of tumour\u2014is there an increased risk of periprosthetic infection by using a <\/b><b>trevira<\/b><b> tube?<\/b> &#8211; Schmolders, Jan ; Koob, Sebastian ; Schepers, Paul ; Kehrer, Michael ; Frey, S\u00f6nke ; Wirtz, Dieter ; Pennekamp, Peter ; Strauss, Andreas International Orthopaedics, 2017, Vol.41(2), pp.423-428 [Peer Reviewed Journal]<\/p>\n<p><b>Lower limb reconstruction in <\/b><b>tumor<\/b><b> patients using modular silver-coated <\/b><b>megaprostheses<\/b><b> with regard to <\/b><b>perimegaprosthetic<\/b><b> joint infection: a case series, including 100 patients and review of the literature &#8211; <\/b>Schmolders, J. ; Koob, S. ; Schepers, P. ; Pennekamp, P. ; Gravius, S. ; Wirtz, D. ; Placzek, R. ; Strauss, A. Archives of Orthopaedic and Trauma Surgery, 2017, Vol.137(2), pp.149-153 [Peer Reviewed Journal]<\/p>\n<p><b>Silver-coated (<\/b><b>Agluna<\/b><b>\u00ae) tumour prostheses can be a protective factor against infection in <\/b><b>high risk<\/b><b> failure patients <\/b>&#8211; Parry, Michael C ; Laitinen, Minna K ; Albergo, Jose I ; Gaston, Czar L ; Stevenson, Jonathan D ; Grimer, Robert J ; Jeys, Lee M European Journal of Surgical Oncology, April 2019, Vol.45(4), pp.704-710 [Peer Reviewed Journal]<\/p>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":4,"featured_media":0,"parent":5602,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"100-width.php","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"class_list":["post-12692","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 5.0.3 - aioseo.com -->\n\t<meta name=\"description\" content=\"SILVER-PORESilver-Pore is an owner technology of surface engineering projected to integrate the silver ions in the implant\u2019s surface. 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